Selenium deficiency can cause epiphyseal plate lesion and decrease cartilage type II collagen production. Selenium (Se) is a vital mineral for the human body to work as an antioxidant and fighting the aging process by improving immunity and lowering the damage that happens by the free radical, Selenium enhancing the body’s resistance against stress, infection, and diseases. As well as modulation of growth and improvement. Shortages in Selenium are affecting more than half of the world’s population. Selenium is one of the rarest elements on the surface of the earth. Selenium introduces in different food systems, the amount in the Selenium depends on the soil-availability to produce those food systems. Selenium found in foods rich in protein because it contains some amino acids.